【ichorbio】の商品一覧
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Bulk anti-Human CD3 Antibody（UCHT-1） ICH1002シリーズ
背景：Anti-CD3 may be used for enumerating immunocompetent T-lymphocytes in peripheral blood. Clone UCHT-1 is also useful in histology for localization of T-lymphocytes in tissue and may be used to enrich T-cells by cell sorting. This T-cell marker has also been used to determine T-versus B-cell lymphomas and leukemias. The UCHT-1 clone is recognized in the human leukocyte differentiation antigen workshop III 471.
85-6822-95, 85-6822-96, 85-6822-97 他
4種類の製品があります
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Bulk anti-Human CD11a antibody（38） ICH1006シリーズ
背景：Anti-CD11a may be used to study a variety of biological phenomena related to the function of cell adhesion molecules. This antibody may be used to study transplantation rejections and to assist in characterizing lymphomas and leukemias.
85-6823-04, 85-6823-05, 85-6823-06 他
4種類の製品があります
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Bulk anti-Human CD11b antibody（ICRF44） ICH1007シリーズ
背景：Anti-CD11b may be used to study lymphocyte subsets in flow cytometry and in cell adhesion research (Mac-1). The antibody may be used to stain tissue sections which have been acetone fixed and frozen.
85-6823-08, 85-6823-09, 85-6823-10 他
4種類の製品があります
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Bulk anti-Human CD16 antibody（3G8） ICH1010シリーズ
背景：CD16 is known as low affinity IgG receptor III (Fc gamma RIII) and is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc gamma RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (Fc gamma RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils.
85-6823-20, 85-6823-21, 85-6823-22 他
4種類の製品があります
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Bulk anti-Human CD56 antibody（ERIC-1） ICH1015シリーズ
背景：Anti-Human CD56 can be used in studies of the neural cell adhesion molecule. This antibody may also be used to study isoforms of NCAM expressed on different tumor types. Anti-CD56 (clone ERIC-1) works well in western blot for analysis of isoforms expressed. Anti-CD56 did not react with any of the leukemias or lymphomas tested
85-6823-52, 85-6823-53, 85-6823-54 他
4種類の製品があります
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Bulk anti-Human EGFR antibody（EGFR.1） ICH1021ULシリーズ
背景：The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor A (TGFA) (note, a full list of the ligands able to activate EGFR and other members of the ErbB family is given in the ErbB article). ErbB2 has no known direct activating ligand, and may be in an activated state constitutively or become active upon heterodimerization with other family members such as EGFR. Upon activation by its growth factor ligands, EGFR undergoes a transition from an inactive monomeric form to an active homodimer - although there is some evidence that preformed inactive dimers may also exist before ligand binding. In addition to forming homodimers after ligand binding, EGFR may pair with another member of the ErbB receptor family, such as ErbB2/Her2/neu, to create an activated heterodimer. There is also evidence to suggest that clusters of activated EGFRs form, although it remains unclear whether this clustering is important for activation itself or occurs subsequent to activation of individual dimers.
85-6823-68, 85-6823-69, 85-6823-70 他
4種類の製品があります
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Bulk anti-Human MHC Class I antibody（W6/32） ICH1023シリーズ
背景：MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in the presentation of antigens to CD8+ T cells and plays a central role in cell-mediated immune responses and tumor surveillance.
85-6823-80, 85-6823-81, 85-6823-82 他
4種類の製品があります
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Bulk anti-Human HLA-DR antibody（L243） ICH1026シリーズ
背景：HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer.
85-6823-96, 85-6823-97, 85-6823-98 他
4種類の製品があります
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Anti-ICAM-1 In Vivo Antibody - Low Endotoxin（15.2）[ICH1027] ICH1027シリーズ
背景：Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
85-6824-01, 85-6824-02, 85-6824-03 他
4種類の製品があります
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Anti-ICAM-1 In Vivo Antibody - Ultra Low Endotoxin（15.2）[ICH1027] ICH1027ULシリーズ
背景：Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
85-6824-05, 85-6824-06, 85-6824-07 他
4種類の製品があります
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Bulk anti-Human CD119 antibody（GIR 208） ICH1028シリーズ
背景：Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
85-6824-09, 85-6824-10, 85-6824-11 他
4種類の製品があります
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Bulk anti-Human CD119 antibody（GIR 208） ICH1028ULシリーズ
背景：Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
85-6824-13, 85-6824-14, 85-6824-15 他
4種類の製品があります
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Bulk anti-Human iNKT cell antibody（6B11） ICH1032シリーズ
背景：Encoded by the TCR V alpha 24-J alpha 18 germline configuration, V alpha 24-J alpha Q is expressed on a subset of NKT cells, namely invariant NKT (iNKT). V alpha 24-J alpha Q TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production.
85-6824-21, 85-6824-22, 85-6824-23 他
4種類の製品があります
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Anti-Mouse 4-1BB In Vivo Antibody - Low Endotoxin（3H3） ICH1036シリーズ
背景：4-1BB (CD137) is a costimulatory molecule expressed on the surface of activated T cells and plays a role in T-cell-mediated proliferative response. 4-1BB signal regulates CD28 co-stimulation in the targeted subset cells to favor Th1 development and maintain long-term cell growth. 4-1BB is also expressed on dendritic cells (DCs) and controls the duration, DC-T interaction, and, therefore, immunogenicity. Clone 3H3 antibody is an agonistic antibody that has been shown to stimulate 4-1BB signaling in vivo.
85-6824-29, 85-6824-30, 85-6824-31 他
4種類の製品があります
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Anti-Mouse 4-1BB In Vivo Antibody - Ultra Low Endotoxin（3H3） ICH1036ULシリーズ
背景：Anti-Mouse CD137/4-1BB clone 3H3 is a monoclonal antibody which reacts with mouse 4-1BB, a TNF receptor superfamily member also known as CD137. The 3H3 antibody has been shown to stimulate 4-1BB signaling in vivo.
85-6824-33, 85-6824-34, 85-6824-35 他
4種類の製品があります
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Anti-Mouse CD80 In Vivo Antibody - Low Endotoxin（16-10A1） ICH1037シリーズ
背景：CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
85-6824-37, 85-6824-38, 85-6824-39 他
4種類の製品があります
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Anti-Mouse CD80 In Vivo Antibody - Ultra Low Endotoxin（16-10A1） ICH1037ULシリーズ
背景：CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
85-6824-41, 85-6824-42, 85-6824-43 他
4種類の製品があります
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Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin（GL1） ICH1038シリーズ
背景：CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the Ig gene superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counterreceptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses in vivo and in vitro.
85-6824-45, 85-6824-46, 85-6824-47 他
4種類の製品があります
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Anti-Mouse CD86 In Vivo Antibody - Ultra Low Endotoxin（GL1） ICH1038ULシリーズ
背景：CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the Ig gene superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counterreceptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses in vivo and in vitro.
85-6824-49, 85-6824-50, 85-6824-51 他
4種類の製品があります
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Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin（500A2） ICH1040シリーズ
背景：CD3 subunits gamma, delta and epsilon are required for proper assembly, trafficking and surface expression of the TCR complex.
85-6824-57, 85-6824-58, 85-6824-59 他
4種類の製品があります
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Anti-Mouse CD3e In Vivo Antibody - Ultra Low Endotoxin（500A2） ICH1040ULシリーズ
背景：CD3 subunits gamma, delta and epsilon are required for proper assembly, trafficking and surface expression of the TCR complex.
85-6824-61, 85-6824-62, 85-6824-63 他
4種類の製品があります
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Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin（145-2C11） ICH1041シリーズ
背景：CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
85-6824-65, 85-6824-66, 85-6824-67 他
4種類の製品があります
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Anti-Mouse CD3e In Vivo Antibody - Ultra Low Endotoxin（145-2C11） ICH1041ULシリーズ
背景：CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
85-6824-69, 85-6824-70, 85-6824-71 他
4種類の製品があります
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Anti-Mouse CD4 In Vivo Antibody - Low Endotoxin（GK1.5） ICH1042シリーズ
背景：CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.
85-6824-73, 85-6824-74, 85-6824-75 他
4種類の製品があります
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Anti-Mouse CD4 In Vivo Antibody - Ultra Low Endotoxin（GK1.5） ICH1042ULシリーズ
背景：CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.
85-6824-77, 85-6824-78, 85-6824-79 他
4種類の製品があります
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Anti-Mouse CD8 beta In Vivo Antibody - Low Endotoxin（53-5.8） ICH1046シリーズ
背景：CD8b is also known as Lyt-3.2 or Ly-3.2. It is a member of the Ig superfamily expressed as a heterodimer with the CD8A chain on a subset of MHC class I-restricted T cells and most thymocytes.
85-6825-06, 85-6825-07, 85-6825-08 他
4種類の製品があります
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Anti-Mouse CD8 beta In Vivo Antibody - Ultra Low Endotoxin（53-5.8） ICH1046ULシリーズ
背景：CD8b is the 32 kD β chain of CD8, also known as Lyt-3.2 or Ly-3.2. It is a member of the Ig superfamily expressed as a heterodimer with the CD8A chain on a subset of MHC class I-restricted T cells and most thymocytes. CD8 is a co-receptor for the TCR complex involved in T cell activation.
85-6825-10, 85-6825-11, 85-6825-12 他
4種類の製品があります
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Anti-Mouse CD11C In Vivo Antibody - Low Endotoxin（N418） ICH1050シリーズ
背景：CD11c is a 150 kD glycoprotein primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells.
85-6825-26, 85-6825-27, 85-6825-28 他
4種類の製品があります
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Anti-Mouse CD25 In Vivo Antibody - Low Endotoxin（PC61） ICH1054シリーズ
背景：IL-2 receptor alpha chain (IL-2Ralpha) is a component of high-affinity IL-2 receptors and thus is a key regulator of lymphocyte proliferation. IL-2R alpha expression occurs at specific stages of early T and B lymphocyte development and is induced upon activation of mature lymphocytes. IL-2R alpha is essential for regulation of both the size and content of the peripheral lymphoid compartment, probably by influencing the balance between clonal expansion and cell death following lymphocyte activation. IL-2Ralpha is also important in the formation of high-affinity binding sites, and the inducibility of the alpha gene contributes to the highly regulated and transient display of high-affinity IL-2R.
85-6825-38, 85-6825-39, 85-6825-40 他
4種類の製品があります
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Anti-Mouse CD25 In Vivo Antibody - Ultra Low Endotoxin（PC61） ICH1054ULシリーズ
背景：IL-2 receptor alpha chain (IL-2Ralpha) is a component of high-affinity IL-2 receptors and thus is a key regulator of lymphocyte proliferation. IL-2R alpha expression occurs at specific stages of early T and B lymphocyte development and is induced upon activation of mature lymphocytes. IL-2R alpha is essential for regulation of both the size and content of the peripheral lymphoid compartment, probably by influencing the balance between clonal expansion and cell death following lymphocyte activation. IL-2Ralpha is also important in the formation of high-affinity binding sites, and the inducibility of the alpha gene contributes to the highly regulated and transient display of high-affinity IL-2R.
85-6825-42, 85-6825-43, 85-6825-44 他
4種類の製品があります
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Anti-Mouse CD45 In Vivo Antibody - Low Endotoxin（I3/2.3） ICH1057シリーズ
背景：CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA). CD45 plays a key role in TCR and BCR signal transduction.
85-6825-62, 85-6825-63, 85-6825-64 他
4種類の製品があります
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Anti-Mouse CD54 In Vivo Antibody - Low Endotoxin（YN1/1.7.4） ICH1059シリーズ
背景：Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
85-6825-66, 85-6825-67, 85-6825-68 他
4種類の製品があります
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Anti-Mouse CD54 In Vivo Antibody - Ultra Low Endotoxin（YN1/1.7.4） ICH1059ULシリーズ
背景：Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
85-6825-70, 85-6825-71, 85-6825-72 他
4種類の製品があります
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Anti-Mouse CD62L In Vivo Antibody - Low Endotoxin（MEL-14） ICH1060シリーズ
背景：CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, and LAM-1. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. Furthermore, CD62L is a cell adhesion molecule that binds to many glycoprotein ligands including CD34, GlyCAM-1, and PSGL-1. Clone MEL-14 is reported as a Nutralization antibody.
85-6825-74, 85-6825-75, 85-6825-76 他
4種類の製品があります
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Anti-Mouse CD115 In Vivo Antibody - Low Endotoxin（AFS98） ICH1068シリーズ
背景：Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.
85-6825-98, 85-6825-99, 85-6826-01 他
4種類の製品があります
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Anti-Mouse CD115 In Vivo Antibody - Ultra Low Endotoxin（AFS98） ICH1068ULシリーズ
背景：Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.
85-6826-03, 85-6826-04, 85-6826-05 他
4種類の製品があります
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Anti-Mouse CD120a In Vivo Antibody - Low Endotoxin（55R-593）[ICH1069] ICH1069シリーズ
背景：Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
85-6826-07, 85-6826-08, 85-6826-09 他
4種類の製品があります
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Anti-Mouse CD40 In Vivo Antibody - Low Endotoxin（FGK4.5） ICH1073シリーズ
背景：CD40, also known as TNFSF5, is a type I transmembrane protein and member of the TNF receptor family. The binding of CD40L (CD40) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 is expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40L is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to "immunodeficiency with hyper-IgM", a disease characterized by failure to produce IgG, IgA and IgE. Some of the early intracellular signaling by the CD4-CD40L system includes the association of the CD40 with TRAFs and the activation of various kinases (4). Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of CD4-CD40L is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
85-6826-11, 85-6826-12, 85-6826-13 他
4種類の製品があります
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Anti-Mouse CD40 In Vivo Antibody - Ultra Low Endotoxin（FGK4.5） ICH1073ULシリーズ
背景：CD40, also known as TNFSF5, is a type I transmembrane protein and member of the TNF receptor family. The binding of CD40L (CD154) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 is expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40L is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to "immunodeficiency with hyper-IgM", a disease characterized by failure to produce IgG, IgA and IgE. Some of the early intracellular signaling by the CD4-CD40L system includes the association of the CD40 with TRAFs and the activation of various kinases (4). Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of CD4-CD40L is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
85-6826-15, 85-6826-16, 85-6826-17 他
4種類の製品があります
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Anti-Mouse CD172a In Vivo Antibody - Low Endotoxin（P84） ICH1076シリーズ
背景：Signal regulatory protein alpha (SIRPalpha), also known as CD172a, is a regulatory membrane type I glycoprotein from the SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.
85-6826-23, 85-6826-24, 85-6826-25 他
4種類の製品があります